OBJECTIVE: The main function of ubiquitin-proteasome system is degradation of the intracellular proteic substance. The ubiquitin-proteasomes systems play magnificent roles in maintenance of many important physiological function in cells. 目的:泛素-蛋白酶体系统主要是对细胞内的异常蛋白质进行降解,对于维持细胞的许多重要生理功能有着极其重要的作用。